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Can spironolactone affect your period? Spironolactone may make your period cycle (menstruation) irregular. Periods may stop altogether or spot bleeding may be experienced in between normal periods. Spironolactone may cause breast changes that are benign (harmless). Enlargement (gynaecomastia), swelling or tenderness of the breasts can occur.
How long do you stay on spironolactone for acne? " It takes about three months for it to start to exert its effect," Dr. Zeichner says — so patience is key. " I generally have patients on this medication for long periods of time, as it only works so long as you are on it."
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